{"product_id":"aentrek","title":"Aentrek 200 (Entrectinib)","description":"\u003cstrong\u003eAentrek\u003c\/strong\u003e(entrectinib) is used to treat a certain type of non-small cell lung cancer (NSCLC) in adults that has spread to other parts of the body. It is also used to treat certain types of solid tumors in adults and children 12 years of age and older that cannot be treated by surgery or that has spread to other parts of the body and that worsened after treatment with other chemotherapy medications. \u003cstrong\u003eAentrek\u003c\/strong\u003e(entrectinib) is in a class of medications called kinase inhibitors. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.\r\n\r\n\u003cstrong\u003e\u003cu\u003eUsage\u003c\/u\u003e\u003c\/strong\u003e\r\n\r\n\u003cstrong\u003eAentrek\u003c\/strong\u003e(entrectinib) comes as a capsule to take by mouth. It is usually taken with or without food once daily. Take \u003cstrong\u003eAentrek\u003c\/strong\u003e(entrectinib)at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand.\r\n\r\nTake \u003cstrong\u003eAentrek\u003c\/strong\u003e(entrectinib) exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.\r\n\r\nSwallow the capsules whole; do not open, chew, or crush them.\r\n\r\nIf you vomit immediately after you take \u003cstrong\u003eAentrek\u003c\/strong\u003e(entrectinib), take another dose as soon as possible.\r\n\r\nAsk your pharmacist or doctor for a copy of the manufacturer's information for the patient.\r\n\r\n\u003cstrong\u003e\u003cu\u003eOther uses for this medicine\u003c\/u\u003e\u003c\/strong\u003e\r\n\r\nThis medication may be prescribed for other uses; ask your doctor or pharmacist for more information.\r\n\r\n\u003cstrong\u003e\u003cu\u003eSpecial precautions should follow\u003c\/u\u003e\u003c\/strong\u003e\r\n\r\n\u003cstrong\u003eBefore taking Aentrek(entrectinib)\u003c\/strong\u003e\r\n\u003cul\u003e\r\n \t\u003cli\u003etell your doctor and pharmacist if you are allergic to \u003cstrong\u003eAentrek\u003c\/strong\u003e(entrectinib), any other medications, or any of the ingredients in \u003cstrong\u003eAentrek\u003c\/strong\u003e(entrectinib) capsules. Ask your pharmacist for a list of the ingredients.\u003c\/li\u003e\r\n \t\u003cli\u003etell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention the following: aprepitant (Emend), certain antifungal medications such as fluconazole (Diflucan), itraconazole (Omel, Sporanox), or ketoconazole; certain medications for arrhythmias such as amiodarone (Nexterone, Pacerone), procainamide, quinidine (in Nuedexta), and sotalol (Betapace, Sorine, Sotylize); azithromycin (Zithromax); clarithromycin (Biaxin, in Prevpac); diltiazem (Cardizem, Tiazac, others); erythromycin (E.E.S., Erythrocin, others); enzalutamide (Xtandi); certain HIV medications such as efavirenz (Sustiva, in Atripla), indinavir (Crixivan), nelfinavir (Viracept), nevirapine (Viramune), ritonavir (Norvir, in Kaletra, others), or saquinavir (Invirase); lithium (Lithobid); modafinil (Provigil); nefazodone; oxcarbazepine (Trileptal); phenobarbital; phenytoin (Dilantin, Phenytek); pioglitazone (Actos, in Actoplus, Duetact, Oseni); rifabutin (Mycobutin); rifampin (Rifadin, Rimactane, in Rifater); oral steroids such as dexamethasone, methylprednisolone (Medrol), and prednisone (Rayos); and verapamil (Calan). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Many other medications may also interact with \u003cstrong\u003eAentrek\u003c\/strong\u003e(entrectinib), so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.\u003c\/li\u003e\r\n \t\u003cli\u003etell your doctor what herbal products you are taking.\u003c\/li\u003e\r\n \t\u003cli\u003etell your doctor if you have or have ever had a nervous system condition, a prolonged QT interval (a rare heart problem that may cause irregular heartbeat, fainting, or sudden death), a slow or irregular heartbeat, a heart attack, heart failure, or heart or liver disease.\u003c\/li\u003e\r\n \t\u003cli\u003etell your doctor if you are pregnant, plan to become pregnant, or if you plan on fathering a child. If you are female, you will need to take a pregnancy test before you start treatment and use birth control to prevent pregnancy during your treatment and for at least 5 weeks after your final dose. If you are a male, you and your partner should use birth control during your treatment with \u003cstrong\u003eAentrek\u003c\/strong\u003e(entrectinib) and for 3 months after your final dose. Talk to your doctor about birth control methods that you can use during your treatment. If you or your partner become pregnant while taking \u003cstrong\u003eAentrek\u003c\/strong\u003e(entrectinib), call your doctor immediately. Entrectinib may harm the fetus.\u003c\/li\u003e\r\n \t\u003cli\u003etell your doctor if you are breastfeeding. You should not breastfeed while you are taking \u003cstrong\u003eAentrek\u003c\/strong\u003e(entrectinib) and for 7 days after the final dose.\u003c\/li\u003e\r\n \t\u003cli\u003eyou should know that \u003cstrong\u003eAentrek\u003c\/strong\u003e(entrectinib)may make cause dizziness or confusion. Do not drive a car or operate machinery until you know how this medication affects you.\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003cstrong\u003e\u003cu\u003eSpecial dietary instructions should I follow\u003c\/u\u003e\u003c\/strong\u003e\r\n\r\nDo not eat grapefruit or drink grapefruit juice while taking this medication.\r\n\r\n\u003cstrong\u003eMissed or forget a dose\u003c\/strong\u003e\r\n\r\nIf you miss a dose by less than 12 hours, take the missed dose as soon as you remember it and then take the next dose at the scheduled time. However, if you miss a dose by more than 12 hours, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.\r\n\r\n\u003cstrong\u003e\u003cu\u003eSide effects can this medication cause?\u003c\/u\u003e\u003c\/strong\u003e\r\n\r\n\u003cstrong\u003eAentrek(entrectinib) may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:\u003c\/strong\u003e\r\n\u003cul\u003e\r\n \t\u003cli\u003etiredness\u003c\/li\u003e\r\n \t\u003cli\u003econstipation\u003c\/li\u003e\r\n \t\u003cli\u003ediarrhea\u003c\/li\u003e\r\n \t\u003cli\u003etaste changes\u003c\/li\u003e\r\n \t\u003cli\u003eheadache\u003c\/li\u003e\r\n \t\u003cli\u003ecough, fever, or other signs of infection\u003c\/li\u003e\r\n \t\u003cli\u003emuscle or joint pain\u003c\/li\u003e\r\n \t\u003cli\u003eback pain\u003c\/li\u003e\r\n \t\u003cli\u003eweight changes\u003c\/li\u003e\r\n \t\u003cli\u003erash\u003c\/li\u003e\r\n \t\u003cli\u003edifficulty falling or staying asleep\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003cstrong\u003eSome side effects can be serious. If you experience any of these symptoms, call your doctor immediately or get emergency medical treatment:\u003c\/strong\u003e\r\n\u003cul\u003e\r\n \t\u003cli\u003edifficulty with learning, memory, attention, or problem solving\u003c\/li\u003e\r\n \t\u003cli\u003emood changes such as anxiety, depression, confusion, or agitation\u003c\/li\u003e\r\n \t\u003cli\u003ebone pain or difficulty moving\u003c\/li\u003e\r\n \t\u003cli\u003evision problems or changes in vision\u003c\/li\u003e\r\n \t\u003cli\u003ejoint pain, stiffness, redness, or swelling\u003c\/li\u003e\r\n \t\u003cli\u003epain in upper right part of the stomach, yellowing of skin or eyes, loss of appetite, or bleeding or bruising easily\u003c\/li\u003e\r\n \t\u003cli\u003eshortness of breath; difficulty breathing when lying down; or swelling of the arms, legs, hands, or feet\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003cstrong\u003eAentrek\u003c\/strong\u003e(entrectinib) may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.","brand":"Tongmeng (Lao) Pharmaceutical \u0026 Food Co., Ltd.（TLPH）","offers":[{"title":"Default Title","offer_id":44797947052075,"sku":"RL14202309011545","price":0.0,"currency_code":"AMD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0701\/3528\/3755\/files\/2023-08-2413.jpg?v=1787022085","url":"https:\/\/xomeds.com\/products\/aentrek","provider":"XOMEDS","version":"1.0","type":"link"}