{"product_id":"cabonni-cabozantinib-80mg-2","title":"Cabonni 80 (Cabozantinib)","description":"\u003cdiv class=\"page-header\"\u003e\r\n\u003cdiv class=\"headers v2 lg\"\u003e\r\n\r\n\u003cstrong\u003eGeneric Name: Cabozantinib\u003c\/strong\u003e\r\n\r\n\u003cstrong\u003eBrand Names: Cabonni (Cabozantinib) 80mg.\u003c\/strong\u003e\r\n\r\n\u003cstrong\u003eDosage form:\u003c\/strong\u003e 80mg x 30Capsules.\r\n\r\n\u003chr\u003e\r\n\r\n\u003c\/div\u003e\r\n\u003c\/div\u003e\r\n\u003cdiv id=\"main-content\" role=\"main\"\u003e\r\n\u003ch2\u003eDescription\u003c\/h2\u003e\r\n\u003cstrong\u003eCabonni (Cabozantinib) \u003c\/strong\u003ecapsule is used to treat medullary thyroid cancer that has already spread to different parts of the body.\r\n\r\n\u003cstrong\u003eCabonni (Cabozantinib)\u003c\/strong\u003e tablet is used alone to treat advanced kidney cancer. It is also used in combination with nivolumab as first-line treatment for advanced kidney cancer.\r\n\r\n\u003cstrong\u003eCabonni (Cabozantinib)\u003c\/strong\u003e tablet is also used to treat a type of liver cancer, called hepatocellular carcinoma, in patients who have been previously treated with other medicines (eg, sorafenib).\r\n\r\n\u003cstrong\u003eCabonni (Cabozantinib)\u003c\/strong\u003e tablet is also used to treat differentiated thyroid cancer that has already spread to different parts of the body, in patients who can no longer be treated with radioactive iodine or not able to receive radioactive iodine, and have been previously treated with other medicines (eg, VEGFR-targeted treatment) but did not work well.\r\n\r\n\u003cstrong\u003eCabonni (Cabozantinib)\u003c\/strong\u003e is an antineoplastic (cancer) medicine. It interferes with the growth of cancer cells, which are eventually destroyed by the body.\r\n\r\nThis medicine is available only with your doctor's prescription.\r\n\r\nThis product is available in the following dosage forms:\r\n\u003cul\u003e\r\n \t\u003cli\u003eCapsule\u003c\/li\u003e\r\n \t\u003cli\u003eTablet\r\n\r\n\u003chr\u003e\r\n\r\n\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003ch2\u003eBefore Using\u003c\/h2\u003e\r\nIn deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:\r\n\u003ch3\u003eAllergies\u003c\/h3\u003e\r\nTell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.\r\n\u003ch3\u003ePediatric\u003c\/h3\u003e\r\nAppropriate studies have not been performed on the relationship of age to the effects of \u003cstrong\u003eCabonni (Cabozantinib)\u003c\/strong\u003e in children younger than 12 years of age to treat differentiated thyroid cancer or in children to treat medullary thyroid cancer, liver cancer, and advanced kidney cancer. Safety and efficacy have not been established.\r\n\u003ch3\u003eGeriatric\u003c\/h3\u003e\r\nAppropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of \u003cstrong\u003eCabonni (Cabozantinib)\u003c\/strong\u003e tablets in the elderly.\r\n\r\nAppropriate studies have not been performed on the relationship of age to the effects of \u003cstrong\u003eCabonni (Cabozantinib)\u003c\/strong\u003e capsules in the geriatric population. However, no geriatric-specific problems have been documented to date.\r\n\u003ch3\u003eBreastfeeding\u003c\/h3\u003e\r\nThere are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.\r\n\u003ch3\u003eDrug Interactions\u003c\/h3\u003e\r\nAlthough certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.\r\n\r\nUsing this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.\r\n\u003cul\u003e\r\n \t\u003cli\u003eAbametapir\u003c\/li\u003e\r\n \t\u003cli\u003eApalutamide\u003c\/li\u003e\r\n \t\u003cli\u003eBoceprevir\u003c\/li\u003e\r\n \t\u003cli\u003eCarbamazepine\u003c\/li\u003e\r\n \t\u003cli\u003eCeritinib\u003c\/li\u003e\r\n \t\u003cli\u003eClarithromycin\u003c\/li\u003e\r\n \t\u003cli\u003eCobicistat\u003c\/li\u003e\r\n \t\u003cli\u003eConivaptan\u003c\/li\u003e\r\n \t\u003cli\u003eEnzalutamide\u003c\/li\u003e\r\n \t\u003cli\u003eFedratinib\u003c\/li\u003e\r\n \t\u003cli\u003eFexinidazole\u003c\/li\u003e\r\n \t\u003cli\u003eFosnetupitant\u003c\/li\u003e\r\n \t\u003cli\u003eFosphenytoin\u003c\/li\u003e\r\n \t\u003cli\u003eIdelalisib\u003c\/li\u003e\r\n \t\u003cli\u003eIndinavir\u003c\/li\u003e\r\n \t\u003cli\u003eItraconazole\u003c\/li\u003e\r\n \t\u003cli\u003eKetoconazole\u003c\/li\u003e\r\n \t\u003cli\u003eLopinavir\u003c\/li\u003e\r\n \t\u003cli\u003eLumacaftor\u003c\/li\u003e\r\n \t\u003cli\u003eMitotane\u003c\/li\u003e\r\n \t\u003cli\u003eNefazodone\u003c\/li\u003e\r\n \t\u003cli\u003eNelfinavir\u003c\/li\u003e\r\n \t\u003cli\u003eNetupitant\u003c\/li\u003e\r\n \t\u003cli\u003ePhenytoin\u003c\/li\u003e\r\n \t\u003cli\u003ePosaconazole\u003c\/li\u003e\r\n \t\u003cli\u003eRifampin\u003c\/li\u003e\r\n \t\u003cli\u003eRitonavir\u003c\/li\u003e\r\n \t\u003cli\u003eSaquinavir\u003c\/li\u003e\r\n \t\u003cli\u003eSt John's Wort\u003c\/li\u003e\r\n \t\u003cli\u003eTelaprevir\u003c\/li\u003e\r\n \t\u003cli\u003eTelithromycin\u003c\/li\u003e\r\n \t\u003cli\u003eVoriconazole\u003c\/li\u003e\r\n \t\u003cli\u003eWarfarin\r\n\r\n\u003chr\u003e\r\n\r\n\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003ch3\u003eOther Interactions\u003c\/h3\u003e\r\nCertain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.\r\n\r\nUsing this medicine with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.\r\n\u003cul\u003e\r\n \t\u003cli\u003eGrapefruit Juice\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003ch3\u003eOther Medical Problems\u003c\/h3\u003e\r\nThe presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:\r\n\u003cul\u003e\r\n \t\u003cli\u003eBleeding problems or\u003c\/li\u003e\r\n \t\u003cli\u003eBlood clots or\u003c\/li\u003e\r\n \t\u003cli\u003eHeart attack, acute or\u003c\/li\u003e\r\n \t\u003cli\u003eHypertension (high blood pressure), uncontrolled or\u003c\/li\u003e\r\n \t\u003cli\u003eHypocalcemia (low calcium levels in the blood) or\u003c\/li\u003e\r\n \t\u003cli\u003eHypothyroidism or\u003c\/li\u003e\r\n \t\u003cli\u003eProteinuria (protein in the urine) or\u003c\/li\u003e\r\n \t\u003cli\u003eStomach fistula or perforation (a hole in the stomach) or\u003c\/li\u003e\r\n \t\u003cli\u003eStroke, recent—Use with caution. May make these conditions worse.\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003cul\u003e\r\n \t\u003cli\u003eDental or tooth problems or\u003c\/li\u003e\r\n \t\u003cli\u003eDental procedures or surgery or\u003c\/li\u003e\r\n \t\u003cli\u003ePoor oral hygiene or\u003c\/li\u003e\r\n \t\u003cli\u003eTooth infection—May increase risk for severe jaw problems.\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003cul\u003e\r\n \t\u003cli\u003eHematemesis (vomiting of blood), recent or\u003c\/li\u003e\r\n \t\u003cli\u003eHemoptysis (coughing up blood), recent or\u003c\/li\u003e\r\n \t\u003cli\u003eHemorrhage (severe bleeding), recent history or\u003c\/li\u003e\r\n \t\u003cli\u003eMelena (black, tarry stools)—Should not be used in patients with these conditions.\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003cul\u003e\r\n \t\u003cli\u003eLiver disease, mild or moderate—Use with caution. The effects may be increased because of slower removal of the medicine from the body.\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003cul\u003e\r\n \t\u003cli\u003eLiver disease, severe—Use is not recommended in patients with these conditions.\r\n\r\n\u003chr\u003e\r\n\r\n\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003ch2\u003eProper Use\u003c\/h2\u003e\r\nMedicines used to treat cancer are very strong and can have many side effects. Before taking this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.\r\n\r\nTake this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of unwanted effects.\r\n\r\nThis medicine comes with a patient information insert. Read and follow the instructions carefully. Ask your doctor if you have any questions.\r\n\r\n\u003cstrong\u003eDo not substitute Cabonni tablets with cabozantinib capsules. Do not substitute Cabonni capsules with cabozantinib tablets.\u003c\/strong\u003e\r\n\r\nTake this medicine on an empty stomach. Do not eat for at least 2 hours before and at least 1 hour after taking this medicine.\r\n\r\nSwallow the medicine whole with a full glass (at least 8 ounces) of water. Do not crush, break, chew, or open the capsule or tablet.\r\n\r\nDo not eat grapefruit or drink grapefruit juice while you are using this medicine. Grapefruit and grapefruit juice may increase the amount of this medicine in the blood.\r\n\r\n\u003chr\u003e\r\n\r\n\u003ch3\u003eDosing\u003c\/h3\u003e\r\nThe dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.\r\n\r\nThe amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.\r\n\u003cul\u003e\r\n \t\u003cli\u003eFor oral dosage form (capsules):\r\n\u003cul\u003e\r\n \t\u003cli\u003eFor thyroid cancer:\r\n\u003cul\u003e\r\n \t\u003cli\u003eAdults—140 milligrams (mg) (one 80 mg and three 20 mg capsules) per day as a single dose. Your doctor may adjust the dose as needed.\u003c\/li\u003e\r\n \t\u003cli\u003eChildren—Use and dose must be determined by your doctor.\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003c\/li\u003e\r\n \t\u003cli\u003eFor oral dosage form (tablets):\r\n\u003cul\u003e\r\n \t\u003cli\u003eFor advanced kidney cancer:\r\n\u003cul\u003e\r\n \t\u003cli\u003eAdults—60 milligrams (mg) once a day. Your doctor may adjust the dose as needed and tolerated.\u003c\/li\u003e\r\n \t\u003cli\u003eChildren—Use and dose must be determined by your doctor.\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003c\/li\u003e\r\n \t\u003cli\u003eFor advanced kidney cancer in combination with nivolumab:\r\n\u003cul\u003e\r\n \t\u003cli\u003eAdults—40 milligrams (mg) once a day. Your doctor may adjust the dose as needed and tolerated.\u003c\/li\u003e\r\n \t\u003cli\u003eChildren—Use and dose must be determined by your doctor.\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003c\/li\u003e\r\n \t\u003cli\u003eFor hepatocellular carcinoma:\r\n\u003cul\u003e\r\n \t\u003cli\u003eAdults—60 milligrams (mg) once a day. Your doctor may adjust the dose as needed and tolerated.\u003c\/li\u003e\r\n \t\u003cli\u003eChildren—Use and dose must be determined by your doctor.\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003c\/li\u003e\r\n \t\u003cli\u003eFor thyroid cancer:\r\n\u003cul\u003e\r\n \t\u003cli\u003eAdults and children 12 years of age and older—Dose is based on body surface area (BSA) and must be determined by your doctor.\r\n\u003cul\u003e\r\n \t\u003cli\u003eBSA of 1.2 meter squared (m2) or more—60 milligrams (mg) once a day. Your doctor may adjust your dose as needed and tolerated.\u003c\/li\u003e\r\n \t\u003cli\u003eBSA of less than 1.2 m2—40 mg once a day. Your doctor may adjust your dose as needed and tolerated.\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003c\/li\u003e\r\n \t\u003cli\u003eChildren younger than 12 years of age—Use and dose must be determined by your doctor.\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003ch3\u003eMissed Dose\u003c\/h3\u003e\r\nIf you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.\r\n\r\nIf you miss a dose of this medicine and it is less than 12 hours until your next scheduled dose, skip the missed dose and take your next dose at the normal time. If you miss a dose and it is more than 12 hours until your next dose, take it as soon as possible and take your next dose at the normal time.\r\n\r\n\u003chr\u003e\r\n\r\n\u003ch3\u003eStorage\u003c\/h3\u003e\r\nStore the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.\r\n\r\nKeep out of the reach of children.\r\n\r\nDo not keep outdated medicine or medicine no longer needed.\r\n\r\nAsk your healthcare professional how you should dispose of any medicine you do not use.\r\n\u003ch2\u003ePrecautions\u003c\/h2\u003e\r\nIt is very important that your doctor check your progress at regular visits to make sure this medicine is working properly. Blood and urine tests may be needed to check for unwanted effects.\r\n\r\nUsing this medicine while you are pregnant can harm your unborn baby. If you are a woman who can get pregnant, you doctor may do tests to make sure you are not pregnant before starting treatment. You should continue to use birth control during treatment with this medicine and for at least 4 months after the last dose to keep from getting pregnant. If you think you have become pregnant while using the medicine, tell your doctor right away.\r\n\r\nCheck with your doctor right away if you have severe stomach pain, gagging, coughing, or choking when you eat or drink. These could be symptoms of a perforation (tear) or fistula (hole) in the bowel.\r\n\r\nThis medicine may increase your risk of bleeding. Tell your doctor right away if you cough up blood or have bleeding gums, difficulty with breathing or swallowing, dizziness, increased menstrual flow or vaginal bleeding, nosebleeds, prolonged bleeding from cuts, red or dark brown urine, or red or black, tarry stools. Stay away from rough sports or other situations where you could be bruised, cut, or injured. Brush and floss your teeth gently. Be careful when using sharp objects, including razors and fingernail clippers.\r\n\r\nThis medicine may increase your risk of developing blood clots. Check with your doctor right away if you have swelling and pain in your arms, legs, or stomach, chest pain, difficulty with breathing, loss of sensation, confusion, or problems with muscle control or speech.\r\n\r\nCheck with your doctor right away if you have chest pain or discomfort, nausea, pain or discomfort in your arms, jaw, back, or neck, sweating, or vomiting. These could be symptoms of a heart attack.\r\n\r\nMake sure any doctor or dentist who treats you knows that you are using this medicine. You may need to stop using this medicine at least 3 weeks before having surgery, including dental procedures. Wait for at least 2 weeks after major surgery, or until adequate wound healing before taking this medicine again.\r\n\r\nYour doctor will check your blood pressure on a regular basis while you are using this medicine. You might need to monitor your blood pressure at home. Tell your doctor right away if you have a severe headache, lightheadedness, or changes in your vision.\r\n\r\nTell your doctor right away if you have jaw tightness, swelling, numbness, pain, or a loose tooth. This could be symptoms of a severe jaw problem.\r\n\r\nThis medicine may cause a serious skin problem called hand-foot syndrome or palmar plantar erythrodysesthesia syndrome. Check with your doctor if you have a rash that does not go away or redness, pain, swelling, or blisters on the palms of your hands or soles of your feet.\r\n\r\nCheck with your doctor right away if you have dark urine, clay-colored stools, stomach pain, or yellow eyes or skin. These may be symptoms of a serious liver problem.\r\n\r\nThis medicine may cause adrenal gland problems. Check with your doctor right away if you have darkening of the skin, diarrhea, dizziness, fainting, loss of appetite, mental depression, nausea, skin rash, unusual tiredness or weakness, or vomiting.\r\n\r\nCheck with your doctor right away if you have a headache, seizures, confusion, blurred vision or other visual problems. These may be symptoms of a rare and serious brain condition called reversible posterior leukoencephalopathy syndrome.\r\n\r\nThis medicine may cause hypocalcemia (low calcium in the blood). Check with your doctor right away if you have confusion, difficulty in breathing, irregular heartbeats, mood or mental changes, muscle cramps in the hands, arms, feet, or face, numbness and tingling around the mouth, fingertips, or feet, seizures, stomach cramps, tremor, or trouble breathing.\r\n\r\nTalk with your doctor before using this medicine if you plan to have children. Some men and women who use this medicine have become infertile (unable to have children).\r\n\r\nDo not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal (eg, St. John's wort) or vitamin supplements.\r\n\r\n\u003chr\u003e\r\n\r\n\u003ch2\u003eSide Effects\u003c\/h2\u003e\r\nAlong with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.\r\n\r\nCheck with your doctor immediately if any of the following side effects occur:\r\n\u003cdiv id=\"ad-mobile-top-container\"\u003e\u003c\/div\u003e\r\n\u003ch4\u003eMore common\u003c\/h4\u003e\r\n\u003col class=\"bullet\"\u003e\r\n \t\u003cli\u003eBlurred vision\u003c\/li\u003e\r\n \t\u003cli\u003eburning, numbness, tingling, or painful sensations\u003c\/li\u003e\r\n \t\u003cli\u003econfusion\u003c\/li\u003e\r\n \t\u003cli\u003econstipation\u003c\/li\u003e\r\n \t\u003cli\u003edark urine\u003c\/li\u003e\r\n \t\u003cli\u003edarkening of the skin\u003c\/li\u003e\r\n \t\u003cli\u003edecreased urination\u003c\/li\u003e\r\n \t\u003cli\u003ediarrhea\u003c\/li\u003e\r\n \t\u003cli\u003edifficulty with breathing or swallowing\u003c\/li\u003e\r\n \t\u003cli\u003edizziness\u003c\/li\u003e\r\n \t\u003cli\u003edry mouth\u003c\/li\u003e\r\n \t\u003cli\u003edry skin and hair\u003c\/li\u003e\r\n \t\u003cli\u003efainting\u003c\/li\u003e\r\n \t\u003cli\u003efeeling cold\u003c\/li\u003e\r\n \t\u003cli\u003ehair loss\u003c\/li\u003e\r\n \t\u003cli\u003eheadache\u003c\/li\u003e\r\n \t\u003cli\u003ehoarseness or husky voice\u003c\/li\u003e\r\n \t\u003cli\u003eincrease in heart rate\u003c\/li\u003e\r\n \t\u003cli\u003elightheadedness\u003c\/li\u003e\r\n \t\u003cli\u003eloss of appetite\u003c\/li\u003e\r\n \t\u003cli\u003emental depression\u003c\/li\u003e\r\n \t\u003cli\u003emuscle cramps, spasms, and stiffness\u003c\/li\u003e\r\n \t\u003cli\u003enausea or vomiting\u003c\/li\u003e\r\n \t\u003cli\u003enervousness\u003c\/li\u003e\r\n \t\u003cli\u003epain in the chest, groin, or legs, especially the calves\u003c\/li\u003e\r\n \t\u003cli\u003epounding in the ears\u003c\/li\u003e\r\n \t\u003cli\u003erapid breathing\u003c\/li\u003e\r\n \t\u003cli\u003eredness, swelling, or pain of the skin\u003c\/li\u003e\r\n \t\u003cli\u003escaling of the skin on the hands and feet\u003c\/li\u003e\r\n \t\u003cli\u003esevere, sudden headache\u003c\/li\u003e\r\n \t\u003cli\u003eskin rash or ulcers\u003c\/li\u003e\r\n \t\u003cli\u003eslow or fast heartbeat\u003c\/li\u003e\r\n \t\u003cli\u003eslurred speech\u003c\/li\u003e\r\n \t\u003cli\u003estomach pain\u003c\/li\u003e\r\n \t\u003cli\u003esudden loss of coordination\u003c\/li\u003e\r\n \t\u003cli\u003esudden, severe weakness or numbness in the arm or leg\u003c\/li\u003e\r\n \t\u003cli\u003esunken eyes\u003c\/li\u003e\r\n \t\u003cli\u003ethirst\u003c\/li\u003e\r\n \t\u003cli\u003eunsteadiness or awkwardness\u003c\/li\u003e\r\n \t\u003cli\u003eunusual tiredness or weakness\u003c\/li\u003e\r\n \t\u003cli\u003evision changes\u003c\/li\u003e\r\n \t\u003cli\u003eweakness in the arms, hands, legs, or feet\u003c\/li\u003e\r\n \t\u003cli\u003eweight gain\u003c\/li\u003e\r\n \t\u003cli\u003ewrinkled skin\u003c\/li\u003e\r\n \t\u003cli\u003eyellow eyes or skin\u003c\/li\u003e\r\n\u003c\/ol\u003e\r\n\u003ch4\u003eLess common\u003c\/h4\u003e\r\n\u003col class=\"bullet\"\u003e\r\n \t\u003cli\u003eBleeding gums\u003c\/li\u003e\r\n \t\u003cli\u003ebloody, black, or tarry stools\u003c\/li\u003e\r\n \t\u003cli\u003ecoughing up blood\u003c\/li\u003e\r\n \t\u003cli\u003eheartburn\u003c\/li\u003e\r\n \t\u003cli\u003eheavy jaw feeling\u003c\/li\u003e\r\n \t\u003cli\u003eincreased menstrual flow or vaginal bleeding\u003c\/li\u003e\r\n \t\u003cli\u003eindigestion\u003c\/li\u003e\r\n \t\u003cli\u003eloosening of a tooth\u003c\/li\u003e\r\n \t\u003cli\u003emood or mental changes\u003c\/li\u003e\r\n \t\u003cli\u003emuscle cramps in the hands, arms, feet, legs, or face\u003c\/li\u003e\r\n \t\u003cli\u003enosebleeds\u003c\/li\u003e\r\n \t\u003cli\u003enumbness and tingling around the mouth, fingertips, or feet\u003c\/li\u003e\r\n \t\u003cli\u003epain, swelling, or numbness in the mouth or jaw\u003c\/li\u003e\r\n \t\u003cli\u003eparalysis\u003c\/li\u003e\r\n \t\u003cli\u003eprolonged bleeding from cuts\u003c\/li\u003e\r\n \t\u003cli\u003ered or dark brown urine\u003c\/li\u003e\r\n \t\u003cli\u003eseizures\u003c\/li\u003e\r\n \t\u003cli\u003esevere stomach pain, cramping, or burning\u003c\/li\u003e\r\n \t\u003cli\u003etremor\u003c\/li\u003e\r\n \t\u003cli\u003etrouble breathing\u003c\/li\u003e\r\n \t\u003cli\u003evomiting of material that looks like coffee grounds, severe and continuing\u003c\/li\u003e\r\n\u003c\/ol\u003e\r\n\u003ch4\u003eRare\u003c\/h4\u003e\r\n\u003col class=\"bullet\"\u003e\r\n \t\u003cli\u003eDisturbed color perception\u003c\/li\u003e\r\n \t\u003cli\u003edouble vision\u003c\/li\u003e\r\n \t\u003cli\u003ehalos around lights\u003c\/li\u003e\r\n \t\u003cli\u003enight blindness\u003c\/li\u003e\r\n \t\u003cli\u003eoverbright appearance of lights\u003c\/li\u003e\r\n \t\u003cli\u003etunnel vision\u003c\/li\u003e\r\n\u003c\/ol\u003e\r\nSome side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:\r\n\u003ch4\u003eMore common\u003c\/h4\u003e\r\n\u003col class=\"bullet\"\u003e\r\n \t\u003cli\u003eBelching\u003c\/li\u003e\r\n \t\u003cli\u003ebleeding after defecation\u003c\/li\u003e\r\n \t\u003cli\u003echange in taste\u003c\/li\u003e\r\n \t\u003cli\u003echanges in hair color\u003c\/li\u003e\r\n \t\u003cli\u003edecreased appetite\u003c\/li\u003e\r\n \t\u003cli\u003edecreased weight\u003c\/li\u003e\r\n \t\u003cli\u003edifficulty having a bowel movement\u003c\/li\u003e\r\n \t\u003cli\u003edifficulty with moving\u003c\/li\u003e\r\n \t\u003cli\u003efear\u003c\/li\u003e\r\n \t\u003cli\u003elack or loss of strength\u003c\/li\u003e\r\n \t\u003cli\u003eloss of taste\u003c\/li\u003e\r\n \t\u003cli\u003emuscle pain\u003c\/li\u003e\r\n \t\u003cli\u003epain in the joints\u003c\/li\u003e\r\n \t\u003cli\u003erash\u003c\/li\u003e\r\n \t\u003cli\u003esore throat\u003c\/li\u003e\r\n \t\u003cli\u003estomach discomfort, upset, or pain\u003c\/li\u003e\r\n \t\u003cli\u003eswelling or inflammation of the mouth\u003c\/li\u003e\r\n \t\u003cli\u003euncomfortable swelling around the anus\u003c\/li\u003e\r\n \t\u003cli\u003evoice changes\u003c\/li\u003e\r\n\u003c\/ol\u003e\r\n\u003c\/div\u003e","brand":"Tongmeng (Lao) Pharmaceutical \u0026 Food Co., Ltd.（TLPH）","offers":[{"title":"Default Title","offer_id":44797947445291,"sku":"RL1420230901327","price":0.0,"currency_code":"AMD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0701\/3528\/3755\/files\/2023-04-1950_2f7a4c3b-48d4-48ea-af1a-6a04b2c908b4.jpg?v=1787022094","url":"https:\/\/xomeds.com\/products\/cabonni-cabozantinib-80mg-2","provider":"XOMEDS","version":"1.0","type":"link"}