{"product_id":"generic-febuxostat-febusodx-40","title":"FEBUSODX 40 (Febuxostat)","description":"\u003ch2\u003eAbout Febuxostat \u003c\/h2\u003e\u003cp\u003eFebuxostat is used to lower hyperuricemia (high uric acid in the blood) in patients with gout who have been treated with allopurinol that did not work well or cannot be treated with allopurinol. This medicine is a xanthine oxidase inhibitor. It works by causing less uric acid to be produced by the body.\u003c\/p\u003e\u003ch2\u003eChronic Gout\u003c\/h2\u003e\u003cp\u003eIndicated for chronic management of hyperuricemia in patients who:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eResponded inadequately to optimal allopurinol therapy\u003c\/li\u003e\n\u003cli\u003eAre intolerant to allopurinol\u003c\/li\u003e\n\u003cli\u003eTreatment with allopurinol not advisable\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eInitial dose: 40 mg PO qDay\u003c\/p\u003e\u003cp\u003eMay increase to 80 mg PO qDay after 2 wk if serum uric acid \u0026lt;6 mg\/dL is not achieved\u003c\/p\u003e\u003ch3\u003eDosage Modifications\u003c\/h3\u003e\u003ch4\u003eRenal impairment\u003c\/h4\u003e\u003cul\u003e\n\u003cli\u003eMild to moderate (CrCl 30-89 mL\/min): No dosage adjustment necessary\u003c\/li\u003e\n\u003cli\u003eSevere (CrCl \u0026lt;30 mL\/min): Not to exceed 40 mg\/day\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch4\u003eHepatic impairment\u003c\/h4\u003e\u003cul\u003e\n\u003cli\u003eMild to moderate (Child-Pugh class A or B): Dosage adjustment not necessary\u003c\/li\u003e\n\u003cli\u003eSevere (Child-Pugh class C): Data not available; use with caution\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch4\u003eProphylaxis for gout flares during treatment\u003c\/h4\u003e\u003cul\u003e\n\u003cli\u003eUpon initiation, recommend for flare prophylaxis with a nonsteroidal anti-inflammatory drug (NSAID) or colchicine\u003c\/li\u003e\n\u003cli\u003eProphylactic therapy may be beneficial for up to 6 months\u003c\/li\u003e\n\u003cli\u003eIf a gout flare occurs, managed gout flare concurrently; treatment does not need to be discontinued\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch3\u003eDosing Considerations\u003c\/h3\u003e\u003cp\u003eLimitation of use: Not recommended for the treatment of asymptomatic hyperuricemia\u003c\/p\u003e\u003cp\u003ePerform serum uric acid level as early as 2 weeks after initiating therapy\u003c\/p\u003e","brand":"BIGBEAR Pharma, Laos PDR","offers":[{"title":"Default Title","offer_id":44797953310763,"sku":"RL3020241020","price":0.0,"currency_code":"AMD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0701\/3528\/3755\/files\/2024-10-1732.jpg?v=1787022198","url":"https:\/\/xomeds.com\/products\/generic-febuxostat-febusodx-40","provider":"XOMEDS","version":"1.0","type":"link"}