{"product_id":"generic-ixazomib-lesadx","title":"ISADX (Ixazomib)","description":"\u003cp\u003eIxazomib is an oral proteasome inhibitor used in the treatment of multiple myeloma. Ixazomib is the first oral second-generation proteasome inhibitor that was approved by the FDA.\u003c\/p\u003e\u003ch2\u003eMultiple Myeloma\u003c\/h2\u003e\u003cp\u003eIndicated in patients who have received at least 1 prior therapy\u003c\/p\u003e\u003cp\u003eUse in combination with lenalidomide and dexamethasone\u003c\/p\u003e\u003cp\u003eContinue treatment until disease progression or unacceptable toxicity\u003c\/p\u003e\u003ch3\u003eStarting doses\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003eIxazomib: 4 mg PO on days 1, 8, and 15 of a 28-day cycle; take 1 hr ac or 2 hr pc\u003c\/li\u003e\n\u003cli\u003eLenalidomide: 25 mg PO on days 1-21 of a 28-day cycle; take with or without food\u003c\/li\u003e\n\u003cli\u003eDexamethasone: 40 mg PO in morning on days 1, 8, 15, and 22 of a 28-day cycle\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch3\u003eDose reductions\u003c\/h3\u003e\u003cul\u003e\u003cli\u003e\n\u003ch4\u003eFor starting dose of 4 mg\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003eFirst reduction: 3 mg\u003c\/li\u003e\n\u003cli\u003eSecond reduction: 2.3 mg\u003c\/li\u003e\n\u003cli\u003eUnable to tolerate 2.3-mg dose: Discontinue therapy\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\u003c\/ul\u003e","brand":"BIGBEAR Pharma, Laos PDR","offers":[{"title":"Default Title","offer_id":44797949509675,"sku":"RL1020230315300","price":0.0,"currency_code":"AMD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0701\/3528\/3755\/files\/2023-09-1798.jpg?v=1787022129","url":"https:\/\/xomeds.com\/products\/generic-ixazomib-lesadx","provider":"XOMEDS","version":"1.0","type":"link"}