{"product_id":"generic-larotrectinib-larotreni-100","title":"Larotreni 100 (Larotrectinib)","description":"\u003cp\u003eLarotrectinib is a treatment for solid cancers that have a neurotrophic tyrosine receptor kinase (NTRK) gene change. You might have larotrectinib for a solid cancer if: your cancer is locally advanced or advanced (metastatic) surgery to remove the cancer could cause severe health problems.\u003c\/p\u003e\u003ch3\u003e\u003cspan id=\"Solid_Tumors\"\u003eSolid Tumors\u003c\/span\u003e\u003c\/h3\u003e\u003cp\u003eIndicated for adults and pediatric patients with solid tumors that have a neurotrophic tyrosine receptor kinase (NTRK) gene fusion without a known acquired resistance mutation, are metastatic or where surgical resection is likely to result in severe morbidity, and have no alternative treatments or have progressed following treatment\u003c\/p\u003e\u003cp\u003e100 mg PO BID\u003c\/p\u003e\u003cp\u003eContinue until disease progression or until unacceptable toxicity\u003c\/p\u003e\u003ch3\u003e\u003cspan id=\"Dosage_Modifications\"\u003eDosage Modifications\u003c\/span\u003e\u003c\/h3\u003e\u003ch4\u003e\u003cspan id=\"Dosage_modifications_for_adverse_reactions\"\u003eDosage modifications for adverse reactions\u003c\/span\u003e\u003c\/h4\u003e\u003cul\u003e\u003cli\u003e\n\u003ch5\u003e\u003cspan id=\"Body_Surface_Area_BSA_1_m2\"\u003eBody Surface Area (BSA) ≥1 m2\u003c\/span\u003e\u003c\/h5\u003e\n\u003cul\u003e\n\u003cli\u003eFirst occurrence: 75 mg BID\u003c\/li\u003e\n\u003cli\u003eSecond occurrence: 50 mg BID\u003c\/li\u003e\n\u003cli\u003eThird occurrence: 100 mg qDay\u003c\/li\u003e\n\u003cli\u003eUnable to tolerate 100 mg qDay: Permanently discontinue\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\u003c\/ul\u003e","brand":"Tongmeng (Lao) Pharmaceutical \u0026 Food Co., Ltd.（TLPH）","offers":[{"title":"Default Title","offer_id":44797951836203,"sku":"RL2020231212933","price":0.0,"currency_code":"AMD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0701\/3528\/3755\/files\/2023-12-1469.jpg?v=1787022161","url":"https:\/\/xomeds.com\/products\/generic-larotrectinib-larotreni-100","provider":"XOMEDS","version":"1.0","type":"link"}