{"product_id":"gienoe-sofosbuvir-velpatasvir-400mg-100mg","title":"Gienoe (Sofosbuvir\/Velpatasvir)","description":"\u003cul\u003e\r\n \t\u003cli\u003e\r\n\u003ch3\u003eBrand name: Gienoe.\u003c\/h3\u003e\r\n\u003c\/li\u003e\r\n \t\u003cli\u003e\r\n\u003ch3\u003eGeneric name: Sofosbuvir+Velpatasvir.\u003c\/h3\u003e\r\n\u003c\/li\u003e\r\n \t\u003cli\u003e\r\n\u003ch3\u003eStrength: 4oomg+100mg\u003c\/h3\u003e\r\n\u003c\/li\u003e\r\n \t\u003cli style=\"text-align: left;\"\u003e\r\n\u003ch3\u003eDosage form: Tablet\u003c\/h3\u003e\r\n\r\n\u003chr\u003e\r\n\r\n\u003ch2\u003e\u003cstrong\u003eIndications\u003c\/strong\u003e\u003c\/h2\u003e\r\n\u003cul\u003e\r\n \t\u003cli\u003eGienoe is a fixed-dose combination drug, including Sofosbuvir (HCVNS5B polymerase Inhibitor, 400mg), and Velpatasvir (HCVNS5A inhibitor, 100mg).\u003c\/li\u003e\r\n \t\u003cli\u003eSuitable for the treatment of adult patients with chronic hepatitis C infection of genotype 1, 2, 3, 4, 5 or 6.\u003c\/li\u003e\r\n \t\u003cli\u003eNo cirrhosis or compensated cirrhosis.\u003c\/li\u003e\r\n \t\u003cli\u003ePlease use ribavirin in combination with decompensated liver cirrhosis.\r\n\r\n\u003chr\u003e\r\n\r\n\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003cstrong\u003eDose and administration method\u003c\/strong\u003e\r\n\u003col\u003e\r\n \t\u003cli\u003eMethod of administration\u003c\/li\u003e\r\n\u003c\/ol\u003e\r\n\u003cul style=\"text-align: center;\"\u003e\r\n \t\u003cli\u003eTest before starting treatment: Screen patients with hepatitis B infection through the test of hepatitis B antigen and antibody.\u003c\/li\u003e\r\n \t\u003cli\u003eRecommended dose: one tablet (400mg Sofosbuvir and 100mg Velpatasvir). oral, Take it once a day, with or without food.\u003c\/li\u003e\r\n \t\u003cli\u003eThe treatment plan and course of treatment for all genotype patients are shown in the following table:\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003ctable class=\" aligncenter\" style=\"height: 189px;\" width=\"611\"\u003e\r\n\u003ctbody\u003e\r\n\u003ctr\u003e\r\n\u003ctd style=\"text-align: center;\" width=\"301\"\u003ePatient Group\u003c\/td\u003e\r\n\u003ctd style=\"text-align: center;\" width=\"301\"\u003eTreatment Plan and Courses\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd width=\"301\"\u003ePatients without cirrhosis and compensated cirrhosis (Child-PughA)\u003c\/td\u003e\r\n\u003ctd width=\"301\"\u003e   Gienoe, 12 weeks\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd width=\"301\"\u003ePatients with decompensated cirrhosis (Child-PughB or C)\u003c\/td\u003e\r\n\u003ctd width=\"301\"\u003e   Gienoe+ribavirin,\r\n\r\n12 weeks\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003c\/tbody\u003e\r\n\u003c\/table\u003e\r\n\u003cul\u003e\r\n \t\u003cli\u003eThere is no dose recommendation for patients with severe kidney injury and end-stage renal disease.\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003col start=\"2\"\u003e\r\n \t\u003cli\u003eDosage specifications\u003c\/li\u003e\r\n\u003c\/ol\u003e\r\n\u003cul\u003e\r\n \t\u003cli\u003eTablets, each containing 400mg Sofosbuvir and 100mg Velpatasvir.\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003col start=\"3\"\u003e\r\n \t\u003cli\u003eContraindications\u003c\/li\u003e\r\n\u003c\/ol\u003e\r\n\u003cul\u003e\r\n \t\u003cli\u003eIf this product is used with ribavirin, the contraindications of ribavirin are also applicable to the two groups together.\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003cstrong\u003eWarnings and Precautions\u003c\/strong\u003e\r\n\u003cul\u003e\r\n \t\u003cli\u003eThe risk of hepatitis B virus reactivation in patients with hepatitis C combined with hepatitis B infection: before using this product, All patients should be tested for hepatitis B virus to find evidence of past or existing infection. Hepatitis B recurrence (Please read this notice carefully and take the medicine according to this notice or under the guidance of a doctor) The case appeared in patients with hepatitis C combined with hepatitis B infection who did not receive hepatitis B antiviral therapy. Some cases eventually Caused hepatitis outbreak, liver failure and even death. During treatment with this product and after completion of treatment, you should Closely monitor the amount of hepatitis B virus.\u003c\/li\u003e\r\n \t\u003cli\u003eWhen this product is taken together with amiodarone, it can cause symptomatic bradycardia: severe symptomatic bradycardia Relief may occur in patients who use amiodarone, especially those who use beta blockers at the same time, or those who suffer from heart disease Patients with onset and\/or advanced liver disease. Co-administration of amiodarone and Gienoe is not recommended. If the patient has no other optionsTreatment options, cardiac monitoring is recommended.\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003cstrong\u003eAdverse reactions\u003c\/strong\u003e\r\n\u003cul\u003e\r\n \t\u003cli\u003e12 weeks of treatment with Gienoe, the most common adverse reactions (incidence rate ≥ 10%, all grades): Headache and fatigue.\u003c\/li\u003e\r\n \t\u003cli\u003eGienoe combined with ribavirin is treated for 12 weeks in patients with decompensated liver cirrhosis, the most common adverse Reactions (incidence ≥10%, all grades): fatigue, anemia, nausea, headache, insomnia and diarrhea.\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003cstrong\u003eStorage method\u003c\/strong\u003e\r\n\u003cul\u003e\r\n \t\u003cli\u003ePlease store at room temperature below 30°C.\u003c\/li\u003e\r\n \t\u003cli\u003ePlease store in the original packaging.\u003c\/li\u003e\r\n \t\u003cli\u003eIf the seal on the bottle mouth is broken or missing, do not use it.\u003c\/li\u003e\r\n \t\u003cli\u003ePlease keep Gienoe and all other medicines out of the reach of children.\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003c\/li\u003e\r\n\u003c\/ul\u003e","brand":"Tongmeng (Lao) Pharmaceutical \u0026 Food Co., Ltd.（TLPH）","offers":[{"title":"Default Title","offer_id":44797947281451,"sku":"RL1420230901445","price":0.0,"currency_code":"AMD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0701\/3528\/3755\/files\/1663315395-6711407eced7a92.png?v=1787022090","url":"https:\/\/xomeds.com\/products\/gienoe-sofosbuvir-velpatasvir-400mg-100mg","provider":"XOMEDS","version":"1.0","type":"link"}