- Details
- Description
INDICATIONS AND USAGE
Afatinib is a kinase inhibitor indicated for:
• First-line treatment of patients with metastatic non-small cell lung cancer (NSCLC) whose tumors have non-resistant epidermal growth factor receptor (EGFR) mutations as detected by an FDA-approved test.
Limitations of Use: Safety and efficacy of LuciAfa were not established in patients whose tumors have resistant EGFR mutations .
• Treatment of patients with metastatic, squamous NSCLC progressing after platinum-based chemotherapy .
DOSAGE AND ADMINISTRATION
• Recommended dosage: 40 mg orally once daily.
• Renal impairment: 30 mg orally once daily in patients with severe renal impairment.
• Instruct patients to take LuciAfa at least 1 hour before or 2 hours after a meal.
